For people who've never been exposed to a good parametric solid modeler there will be a lot of "wow" moments. Not quite like a ride in a Ferrari (Catia), but definitely like a spin in a good fast Mustang. Once you see what can be done using design tables, equations, and global variables to control the shape of things, your life will be changed forever.
It should be mentioned that a full SW license starts at about $4K per seat. Maybe that Blender interface isn't quite so tough after all...
The Alibre personal at $199 will likely be the most interesting commercial product to Makers. It will export STL's.
I also saw a Sketchup plugin called Driving Dimensions which adds parametric features to Sketchup, available in both a crippled free version and a paid version.
Also, for anybody with some Python chops
Freecad is totally free and open source.
-Jim Hart